Comparative effectiveness research (CER) identifies what works best for whom under what circumstances. Congress, in the American Recovery and Reinvestment Act (ARRA) of 2009, tasked the Institute of Medicine (IOM) to recommend national priorities for research questions to be addressed by CER and supported by ARRA funds. In its 2009 report, Initial National Priorities for Comparative Effectiveness Research, the authoring committee establishes a working definition of CER, develops a priority list of research topics to be undertaken with ARRA
funding using broad stakeholder input, and identifies the necessary requirements to support a robust and sustainable CER enterprise. The full list of priorities and recommendations can be found online and include many preventive measures:
Compare the effectiveness of primary prevention methods, such as exercise and balance training, versus clinical treatments in preventing falls in older adults at varying degrees of risk.
Compare the effectiveness of school-based interventions involving meal programs, vending machines, and physical education, at different levels of intensity, in preventing and treating overweight and obesity in children and adolescents.
Compare the effectiveness of interventions (e.g., community-based multi-level interventions, simple health education, usual care) to reduce health disparities in cardiovascular disease, diabetes, cancer, musculoskeletal diseases, and birth outcomes.
The TOXMAP widget allows you to launch a TOXMAP search from your blog, wiki, or Web page. Enter a ZIP code into the widget to see a map of Toxic Release Inventory facilities and Superfund NPL sites, or click "More info" to go to the TOXMAP home page.
The TOXMAP Toolbar lets you search TRI releases, Superfund National Priorities List (NPL) sites by contaminant, or TRI facilities and Superfund NPL sites by ZIP code -- all from your browser search box.
TOXMAP also has updated mortality data to "layer" onto your map.
As of Friday, May 22, the Public Health Library will be open Monday-Friday, 9am to 5pm.
Wednesday May 20 is the last day we will be open in the evening; on Thursday, May 21, we will close at 5pm. Evening and weekend hours will resume in the fall.
Enjoy your summer!
The first issue of PLoS Medicine, published by the Public Library of Science, came out about five years ago. Its aim at the time was to provide an open-access alternative to top-tier subscription medical journals such as the New England Journal of Medicine and The Lancet. They have also tried to distinguish PLoS Medicine from other journals in several ways. In this regard, one distinguishing feature of PLoS Medicine is a ban on advertisements for drugs or medical devices.
Another stated aim was to be a journal that had a clear priority of publishing papers on diseases that take the greatest toll on health globally. The editiorial in the latest issue reaffirms and adds to this by stating PLoS Medicine "will take an evidence-based approach to identifying topics of global health priority, and will give highest priority to publishing studies that advance human health in these areas."
Take a read!
The latest issue (April, 2009) includes these research articles:
Mortality of HIV-Infected Patients Starting Antiretroviral Therapy in Sub-Saharan Africa: Comparison with HIV-Unrelated Mortality
Influence of Rapid Malaria Diagnostic Tests on Treatment and Health Outcome in Fever Patients, Zanzibar?A Crossover Validation Study
Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria
If you are interested in publishing in PLoS Medicine, please go to their web site for information.